Comparative analysis of integrative and conjugative mobile genetic elements in the genus Mesorhizobium.

ABSTRACT: Members of the Mesorhizobium genus are soil bacteria that often form nitrogen-fixing symbioses with legumes. Most characterised Mesorhizobium spp. genomes are ~8 Mb in size and harbour extensive pangenomes including large integrative and conjugative elements (ICEs) carrying genes required for symbiosis (ICESyms). Here, we document and compare the conjugative mobilome of 41 complete Mesorhizobium genomes. We delineated 56 ICEs and 24 integrative and mobilizable elements (IMEs) collectively occupying 16 distinct integration sites, along with 24 plasmids. We also demonstrated horizontal transfer of the largest (853,775 bp) documented ICE, the tripartite ICEMspSym^AA22. The conjugation systems of all identified ICEs and several plasmids were related to tho

SUBMITTER: Colombi E 

PROVIDER: S-EPMC8627217 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature