Arthralgia resolution rate following chikungunya virus infection.

ABSTRACT:

Background

Arthralgia, persistent pain or stiffness of the joints, is the hallmark symptom of chronic chikungunya virus (CHIKV) disease. Associated with significant disability and reduced quality of life, arthralgia can persist for many months following CHIKV infection. Understanding the expected duration of arthralgia persistence is important for managing clinical expectations at the individual-level as well as for estimating long-term burdens on population health following a CHIKV epidemic.

Methods

A review of cohort studies reporting the prevalence of arthralgia post-CHIKV infection over multiple time points was conducted. Generalized linear models were used to estimate the average rate of arthralgia resolution following CHIKV infection.

Results

Sixteen cohort stud

SUBMITTER: O'Driscoll M 

PROVIDER: S-EPMC8627389 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature