Renal outcomes of diabetic patients treated with combination therapy of ACE inhibitors plus either thiazide diuretics or calcium channel blockers: comparative retrospective cohort study in Northwestern Ethiopia.

ABSTRACT:

Objective

The study determined the comparative renal functions on patients with diabetes treated with ACE inhibitors (ACEIs) plus either thiazide diuretics or calcium channel blockers (CCBs) in Northwestern Ethiopia.

Design

Retrospective cohort study design was employed to collect the data from medical records of patients with diabetes followed for 1-5 years (N=404).

Setting

The medical records of patients in chronic diabetic follow-up clinics of the hospital.

Participants

All the patients with diabetes medical records in Northwestern Ethiopian specialised hospital.

Main outcome measures

Exposures were ACEIs plus thiazide diuretics or CCBs collected from March to June 2020. Outcomes were defined as declining in estimated glomerular filtration rate (eGFR)

SUBMITTER: Netere AK 

PROVIDER: S-EPMC8627402 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature