Urinary concentrations of phenols, parabens, and triclocarban in relation to uterine leiomyomata incidence and growth.

ABSTRACT:

Objective

To examine the association of urinary concentrations of phenols, parabens, and triclocarban with incidence and growth of uterine leiomyomata (UL; fibroids).

Design

Case-cohort study, nested within the Study of Environment, Lifestyle, and Fibroids, a prospective cohort study.

Setting

Clinic visits at baseline and every 20 months for 60 months.

Patient(s)

754 Black women aged 23-35 years residing in the Detroit, Michigan area (enrolled during 2010-2012).

Intervention

None.

Main outcome measure(s)

At each study visit, women underwent transvaginal ultrasound for measurement of UL incidence and growth and provided urine specimens in which we quantified concentrations of seven phenols, four parabens, and triclocarban. We used Cox proportional

SUBMITTER: Wesselink AK 

PROVIDER: S-EPMC8627427 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature