LVAD decommissioning for myocardial recovery: Long-term ventricular remodeling and adverse events.

ABSTRACT:

Background

Left ventricular assist devices (LVADs) mechanically unload the heart and coupled with neurohormonal therapy can promote reverse cardiac remodeling and myocardial recovery. Minimally invasive LVAD decommissioning with the device left in place has been reported to be safe over short-term follow-up. Whether device retention reduces long-term safety, or sustainability of recovery is unknown.

Methods

This is a dual-center retrospective analysis of patients who had achieved responder status (left ventricular ejection fraction, LVEF ≥40% and left ventricular internal diastolic diameter, LVIDd ≤6.0 cm) and underwent elective LVAD decommissioning for myocardial recovery from May 2010 to January 2020. All patients had outflow graft closure and driveline resection with the

SUBMITTER: Gerhard EF 

PROVIDER: S-EPMC8627486 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature