Subtelomeres are fast-evolving regions of the Streptomyces linear chromosome.

ABSTRACT: Streptomyces possess a large linear chromosome (6-12 Mb) consisting of a conserved central region flanked by variable arms covering several megabases. In order to study the evolution of the chromosome across evolutionary times, a representative panel of Streptomyces strains and species (125) whose chromosomes are completely sequenced and assembled was selected. The pan-genome of the genus was modelled and shown to be open with a core-genome reaching 1018 genes. The evolution of Streptomyces chromosome was analysed by carrying out pairwise comparisons, and by monitoring indexes measuring the conservation of genes (presence/absence) and their synteny along the chromosome. Using the phylogenetic depth offered by the chosen panel, it was possible to infer that within the c

SUBMITTER: Lorenzi JN 

PROVIDER: S-EPMC8627663 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature