Smartphone-integrated colorimetric sensor array-based reader system and fluorometric detection of dopamine in male and female geriatric plasma by bluish-green fluorescent carbon quantum dots.

ABSTRACT: A simple, cost-effective system was developed for dopamine (DA) detection using green synthesized 1-6 ​nm honey-based carbon quantum dots (H-CQDs) exhibiting bluish green fluorescence. The H-CQDs exhibited emission at 445 ​nm, with a quantum yield of ∼44%. The H-CQDs were used as a probe for electron transfer based DA detection and changes in H-CQD color in the presence of DA. The H-CQDs were formed with polar functional groups and were highly soluble in aqueous media. In the fluorometric mode, the proposed system demonstrated high specificity toward DA and effective limit of detection (LOD) values of 6, 8.5, and 8 ​nM in deionized (DI) water, male geriatric plasma, and female geriatric plasma, respectively, in the linear range 100 ​nM-1000 μM. In the colorimetric mode, the color changed w

SUBMITTER: Chellasamy G 

PROVIDER: S-EPMC8628042 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature