Patient-Reported Nausea and Fatigue Related to Methotrexate: A Prospective, Self-Controlled Study in the ArthritisPower^® Registry.

ABSTRACT:

Introduction

The magnitude and frequency of temporally related methotrexate (MTX)-associated side effects in rheumatoid arthritis (RA) or psoriatic arthritis (PsA) patients are difficult to quantify using traditional research methods. As proof of concept designed in part to implement digital data collection for remote patient monitoring, we conducted a study implementing self-controlled case series analytic methods to understand MTX-related symptoms in RA or PsA.

Methods

In study phase 1, adults with RA or PsA from the ArthritisPower^® Registry (past or current oral MTX users) participated in a cross-sectional survey. In phase 2, current MTX users participated in a longitudinal study and completed the Patient-Reported Outcomes Measurement Information System (PROMIS

SUBMITTER: Nowell WB 

PROVIDER: S-EPMC8628141 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature