Clinical Features and Outcomes of Combined Pulmonary Fibrosis and Emphysema After Lung Transplantation.

ABSTRACT:

Background

Combined pulmonary fibrosis and emphysema (CPFE) is recognized as a characteristic syndrome of smoking-related interstitial lung disease that has a worse prognosis than idiopathic pulmonary fibrosis (IPF). However, outcomes after lung transplantation for CPFE have not been reported. The aim of this study is to describe the clinical features and outcomes of CPFE after lung transplantation.

Research question

What are the clinical features and outcomes of CPFE after lung transplantation?

Study design and methods

This is a single-center retrospective cohort study of patients with CPFE and IPF who underwent lung transplantation at our center between January 2011 and December 2016. We defined CPFE as ≥10% emphysema in the upper lung fields combined with fibrosis

SUBMITTER: Takahashi T 

PROVIDER: S-EPMC8628179 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature