Prenatal household air pollutant exposure is associated with reduced size and gestational age at birth among a cohort of Ghanaian infants.

ABSTRACT:

Background

Low birth weight and prematurity are important risk factors for death and disability, and may be affected by prenatal exposure to household air pollution (HAP).

Methods

We investigate associations between maternal exposure to carbon monoxide (CO) during pregnancy and birth outcomes (birth weight, birth length, head circumference, gestational age, low birth weight, small for gestational age, and preterm birth) among 1288 live-born infants in the Ghana Randomized Air Pollution and Health Study (GRAPHS). We evaluate whether evidence of malaria during pregnancy, as determined by placental histopathology, modifies these associations.

Results

We observed effects of CO on birth weight, birth length, and gestational age that were modified by placental malarial stat

SUBMITTER: Quinn AK 

PROVIDER: S-EPMC8628363 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature