Predicting long-term postsurgical pain by examining the evolution of acute pain.

ABSTRACT:

Background

Increased acute postoperative pain intensity has been associated with the development of persistent postsurgical pain (PPP) in mechanistic and clinical investigations, but it remains unclear which aspects of acute pain explain this linkage.

Methods

We analysed clinical postoperative pain intensity assessments using symbolic aggregate approximations (SAX), a graphical way of representing changes between pain states from one patient evaluation to the next, to visualize and understand how pain intensity changes across sequential assessments are associated with the intensity of postoperative pain at 1 (M1) and 6 (M6) months after surgery. SAX-based acute pain transition patterns were compared using cosine similarity, which indicates the degree to which patterns mirror

SUBMITTER: Smith CR 

PROVIDER: S-EPMC8628519 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature