Raman spectroscopic analysis of skin as a diagnostic tool for Human African Trypanosomiasis.

ABSTRACT: Human African Trypanosomiasis (HAT) has been responsible for several deadly epidemics throughout the 20th century, but a renewed commitment to disease control has significantly reduced new cases and motivated a target for the elimination of Trypanosoma brucei gambiense-HAT by 2030. However, the recent identification of latent human infections, and the detection of trypanosomes in extravascular tissues hidden from current diagnostic tools, such as the skin, has added new complexity to identifying infected individuals. New and improved diagnostic tests to detect Trypanosoma brucei infection by interrogating the skin are therefore needed. Recent advances have improved the cost, sensitivity and portability of Raman spectroscopy technology for non-invasive medical diagnostics, making it an attr

SUBMITTER: Girard A 

PROVIDER: S-EPMC8629383 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature