Effect of dietary fat intake and genetic risk on glucose and insulin-related traits in Brazilian young adults.

ABSTRACT:

Purpose

The development of metabolic diseases such as type 2 diabetes (T2D) is closely linked to a complex interplay between genetic and dietary factors. The prevalence of abdominal obesity, hyperinsulinemia, dyslipidaemia, and high blood pressure among Brazilian adolescents is increasing and hence, early lifestyle interventions targeting these factors might be an effective strategy to prevent or slow the progression of T2D.

Methods

We aimed to assess the interaction between dietary and genetic factors on metabolic disease-related traits in 200 healthy Brazilian young adults. Dietary intake was assessed using 3-day food records. Ten metabolic disease-related single nucleotide polymorphisms (SNPs) were used to construct a metabolic-genetic risk score (metabolic-GRS).

Resul

SUBMITTER: Alsulami S 

PROVIDER: S-EPMC8630327 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature