Association of Maternal Sexually Transmitted Infections With Risk of Preterm Birth in the United States.

ABSTRACT:

Importance

Maternal infection has been implicated in the pathogenesis of preterm birth through intrauterine inflammatory response. Chlamydia, gonorrhea, and syphilis are among the most common sexually transmitted infections worldwide, but studies on their association with preterm birth are sparse.

Objective

To examine the association between maternal chlamydia, gonorrhea, and syphilis infections in pregnancy and the risk of preterm birth in a large population-based study in the US.

Design, setting, and participants

This population-based retrospective cohort study examined nationwide birth certificate data from the US National Vital Statistics System between 2016 and 2019. All mothers who had a singleton live birth and available data on chlamydia, gonorrhea, or syphili

SUBMITTER: Gao R 

PROVIDER: S-EPMC8630565 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature