In Vitro Folliculogenesis in Mammalian Models: A Computational Biology Study.

ABSTRACT: In vitro folliculogenesis (ivF) has been proposed as an emerging technology to support follicle growth and oocyte development. It holds a great deal of attraction from preserving human fertility to improving animal reproductive biotechnology. Despite the mice model, where live offspring have been achieved,in medium-sized mammals, ivF has not been validated yet. Thus, the employment of a network theory approach has been proposed for interpreting the large amount of ivF information collected to date in different mammalian models in order to identify the controllers of the in vitro system. The WoS-derived data generated a scale-free network, easily navigable including 641 nodes and 2089 links. A limited number of controllers (7.2%) are responsible for networ

SUBMITTER: Bernabo N 

PROVIDER: S-EPMC8630647 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature