Design, analysis, and reporting of pilot studies in HIV: a systematic review and methodological study.

ABSTRACT:

Background

Pilot studies are essential in determining if a larger study is feasible. This is especially true when targeting populations that experience stigma and may be difficult to include in research, such as people with HIV. We sought to describe how pilot studies have been used to inform HIV clinical trials.

Methods

We conducted a methodological study of pilot studies of interventions in people living with HIV published until November 25, 2020, using Medline, Embase, and Cochrane Controlled Register of Trials (CENTRAL). We extracted data on their nomenclature, primary objective, use of progression criteria, sample size, use of qualitative methods, and other contextual information (region, income, level, type of intervention, study design).

Results

Our search retr

SUBMITTER: El-Khechen HA 

PROVIDER: S-EPMC8630899 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature