Viral Haplotypes in COVID-19 Patients Associated With Prolonged Viral Shedding.

ABSTRACT:

Background

Recently, more patients who recovered from the novel coronavirus disease 2019 (COVID-19) may later test positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) again using reverse transcription-polymerase chain reaction (RT-PCR) testing. Even though it is still controversial about the possible explanation for clinical cases of long-term viral shedding, it remains unclear whether the persistent viral shedding means re-infection or recurrence.

Methods

Specimens were collected from three COVID-19-confirmed patients, and whole-genome sequencing was performed on these clinical specimens during their first hospital admission with a high viral load of SARS-CoV-2. Laboratory tests were examined and analyzed throughout the whole course of the disease. Phy

SUBMITTER: Wu Y 

PROVIDER: S-EPMC8631178 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature