Consensus Guidelines for Improving Quality of Assessment and Training for Neuromuscular Diseases.

ABSTRACT: Critical components of successful evaluation of clinical outcome assessments (COAs) in multisite clinical trials and clinical practice are standardized training, administration, and documented reliability of scoring. Experiences of evaluators, alongside patient differences from regional standards of care, may contribute to heterogeneity in clinical center's expertise. Achieving low variability and high reliability of COA is fundamental to clinical research and to give confidence in our ability to draw rational, interpretable conclusions from the data collected. The objective of this manuscript is to provide a framework to guide the learning process for COAs for use in clinics and clinical trials to maximize reliability and validity of COAs in neuromuscular disease (NMD). This is a consensu

SUBMITTER: Duong T 

PROVIDER: S-EPMC8631528 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature