Association of Serum Galectin-3-Binding Protein and Metabolic Syndrome in a Chinese Adult Population.

ABSTRACT:

Background

Galectin-3-binding protein (GAL-3BP) is a ubiquitous and multifunctional secreted glycoprotein, which functions in innate immunity and has been highlighted as a potential mediator of adipose inflammation in obesity. In this study, we aimed to identify whether GAL-3BP is a novel biological marker for metabolic syndrome (MetS).

Methods

The biochemical and anthropometric variables of the 570 participants in this study were evaluated using standard procedures. Their serum GAL-3BP levels were measured using enzyme-linked immunosorbent assay (ELISA), while the association between the glycoprotein and MetS was analyzed using multiple logistic regression analyses. Moreover, an experimental MetS model was established. The expression of GAL-3BP in serum and adipose tissue w

SUBMITTER: Zhen S 

PROVIDER: S-EPMC8631730 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature