Efficacy and Safety of Ashwagandha Root Extract on Cognitive Functions in Healthy, Stressed Adults: A Randomized, Double-Blind, Placebo-Controlled Study.

ABSTRACT:

Background

The global prevalence of stress is increasing. Stress adversely affects cognitive ability, sleep quality, and overall psychological well-being. Ashwagandha (Withania somnifera (L.) Dunal), an essential medicine in Ayurveda, is reportedly beneficial in reducing stress and improving memory. This double-blind, randomized, placebo-controlled clinical study evaluated the effect of Ashwagandha root extract sustained-release capsule 300 mg (Prolanza™; hereafter Ashwagandha SR) on cognitive functions, stress levels, sleep quality, overall well-being, and safety in stressed subjects.

Methods

Subjects (130 healthy cognitively sound adults [20-55 years, body mass index:18-29 kg/m²]) having a Perceived Stress Scale (PSS) score of 14-24 were randomized to rec

SUBMITTER: Gopukumar K 

PROVIDER: S-EPMC8632422 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature