A pilot study of high-intensity interval training in older adults with treatment naive chronic lymphocytic leukemia.

ABSTRACT: Chronic lymphocytic leukemia (CLL) is the most common leukemia in the USA, affecting predominantly older adults. CLL is characterized by low physical fitness, reduced immunity, and increased risk of secondary malignancies and infections. One approach to improving CLL patients' physical fitness and immune functions may be participation in a structured exercise program. The aims of this pilot study were to examine physical and immunological changes, and feasibility of a 12-week high-intensity interval training (HIIT) combined with muscle endurance-based resistance training on older adults with treatment naïve CLL. We enrolled eighteen participants with CLL aged 64.9 ± 9.1 years and assigned them to groups depending on distance lived from our fitness center. Ten participants (4 M/6F) complete

SUBMITTER: MacDonald G 

PROVIDER: S-EPMC8633014 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature