Multisite investigation of strategies for the clinical implementation of pre-emptive pharmacogenetic testing.

ABSTRACT:

Purpose

The increased availability of clinical pharmacogenetic (PGx) guidelines and decreasing costs for genetic testing have slowly led to increased utilization of PGx testing in clinical practice. Pre-emptive PGx testing, where testing is performed in advance of drug prescribing, is one means to ensure results are available at the time of prescribing decisions. However, the most efficient and effective methods to clinically implement this strategy remain unclear.

Methods

In this report, we compare and contrast implementation strategies for pre-emptive PGx testing by 15 early-adopter institutions. We surveyed these groups, collecting data on testing approaches, team composition, and workflow dynamics, in addition to estimated third-party reimbursement rates.

Results

SUBMITTER: Duarte JD 

PROVIDER: S-EPMC8633054 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature