Lymph node status and its impact on the prognosis of left-sided and right-sided colon cancer: A SEER population-based study.

ABSTRACT:

Background

Some significant differences exist between the outcomes of left- and right-sided colon cancer patients. The presence of nodal metastases is a critical prognostic factor, especially in the absence of distant metastasis. Our research studied the lymph nodes status of left- and right-sided colon cancer patients to determine the influence of this factor on prognosis.

Methods

Our data were obtained from the Surveillance, Epidemiology and End Results (SEER) database. We used the chi-square test to analyze the clinicopathological characteristics. The X-tile program was adopted to acquire optimal cutoff points of lymph node index. Kaplan-Meier curves were used to analyze prognosis and multivariate Cox regression models were performed to identify the independent factors as

SUBMITTER: Huang Y 

PROVIDER: S-EPMC8633222 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature