Dietary Patterns and Associated Microbiome Changes that Promote Oncogenesis.

ABSTRACT: The recent increases in cancer incidences have been linked to lifestyle changes that result in obesity and metabolic syndrome. It is now evident that these trends are associated with the profound changes that occur in the intestinal microbiome, producing altered microbial population signatures that interact, directly or indirectly, with potentially pro-carcinogenic molecular pathways of transcription, proliferation, and inflammation. The effects of the entire gut microbial population on overall health are complex, but individual bacteria are known to play important and definable roles. Recent detailed examinations of a large number of subjects show a tight correlation between habitual diets, fecal microbiome signatures, and markers of metabolic health. Diets that score higher in healthfuln

SUBMITTER: Ibragimova S 

PROVIDER: S-EPMC8633417 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature