Predicting Alcohol Dependence Symptoms by Young Adulthood: A Co-Twin Comparisons Study.

ABSTRACT: Co-twin comparisons address familial confounding by controlling for genetic and environmental influences that twin siblings share. We applied the co-twin comparison design to investigate associations of adolescent factors with alcohol dependence (AD) symptoms. Participants were 1286 individuals (581 complete twin pairs; 42% monozygotic; and 54% female) from the FinnTwin12 study. Predictors included adolescent academic achievement, substance use, externalizing problems, internalizing problems, executive functioning, peer environment, physical health, relationship with parents, alcohol expectancies, life events, and pubertal development. The outcome was lifetime AD clinical criterion count, as measured in young adulthood. We examined associations of each adolescent domain with AD symptoms in

SUBMITTER: Stephenson M 

PROVIDER: S-EPMC8634152 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature