The Deficits of Individual Morphological Covariance Network Architecture in Schizophrenia Patients With and Without Violence.

ABSTRACT: Background: Schizophrenia is associated with a significant increase in the risk of violence, which constitutes a public health concern and contributes to stigma associated with mental illness. Although previous studies revealed structural and functional abnormalities in individuals with violent schizophrenia (VSZ), the neural basis of psychotic violence remains controversial. Methods: In this study, high-resolution structural magnetic resonance imaging (MRI) data were acquired from 18 individuals with VSZ, 23 individuals with non-VSZ (NSZ), and 22 age- and sex-matched healthy controls (HCs). Whole-brain voxel-based morphology and individual morphological covariance networks were analysed to reveal differences in gray matter volume (GMV) and individual morphological covariance

SUBMITTER: Shen D 

PROVIDER: S-EPMC8634443 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature