Expanding Criteria for Prognostic Stage IA in Hormone Receptor-Positive Breast Cancer.

ABSTRACT:

Background

The prognostic significance of patients with low-risk recurrence score (RS) results in the context of the American Joint Committee on Cancer (AJCC) eighth edition pathologic prognostic staging has not been investigated. We evaluated if expanded RS criteria can be considered for downstaging in AJCC pathologic prognostic staging.

Methods

Using Surveillance, Epidemiology, and End Results data, we identified patients with T1-3N0-3M0 hormone receptor-positive, HER2-negative breast cancer treated from 2010 to 2015 with follow-up data through 2016. We evaluated TNM categories, grade, and RS result. The primary outcome measured was 5-year disease-specific survival (DSS) of patients with low-risk RS results not already pathologic prognostic stage IA, determined by T and N

SUBMITTER: Kantor O 

PROVIDER: S-EPMC8634483 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature