Nutritional Metabolomics and the Classification of Dietary Biomarker Candidates: A Critical Review.

ABSTRACT: Recent advances in metabolomics allow for more objective assessment of contemporary food exposures, which have been proposed as an alternative or complement to self-reporting of food intake. However, the quality of evidence supporting the utility of dietary biomarkers as valid measures of habitual intake of foods or complex dietary patterns in diverse populations has not been systematically evaluated. We reviewed nutritional metabolomics studies reporting metabolites associated with specific foods or food groups; evaluated the interstudy repeatability of dietary biomarker candidates; and reported study design, metabolomic approach, analytical technique(s), and type of biofluid analyzed. A comprehensive literature search of 5 databases (PubMed, EMBASE, Web of Science, BIOSIS, and CINAHL) wa

SUBMITTER: Rafiq T 

PROVIDER: S-EPMC8634495 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature