Risk of Transmission and Viral Shedding From the Time of Infection for Respiratory Syncytial Virus in Households.

ABSTRACT: Respiratory syncytial virus (RSV) is a leading cause of lower respiratory tract infection worldwide, but reports of temporal changes in the risk of transmission among close contacts has been scarce. This study aimed to examine an association between the viral load trajectory and transmission risk to develop a better control strategy for the disease spread. We conducted a household-based prospective cohort study in Biliran Province, the Philippines, and enrolled 451 participants to observe the development of acute respiratory infection. Including the cases found at the health-care facility, we analyzed the data of viral loads with symptom records obtained from 172 followed participants who had household member positive for RSV with a rapid test during an RSV outbreak in 2018-2019. We develo

SUBMITTER: Otomaru H 

PROVIDER: S-EPMC8634588 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature