Proportional Changes in Cognitive Subdomains During Normal Brain Aging.

ABSTRACT: Background: Neuroscience lacks a reliable method of screening the early stages of dementia. Objective: To improve the diagnostics of age-related cognitive functions by developing insight into the proportionality of age-related changes in cognitive subdomains. Materials and Methods: We composed a battery of psychophysiological tests and collected an open-access psychophysiological outcomes of brain atrophy (POBA) dataset by testing individuals without dementia. To extend the utility of machine learning (ML) classification in cognitive studies, we proposed estimates of the disproportional changes in cognitive functions: an index of simple reaction time to decision-making time (ISD), ISD with the accuracy performance (ISDA), and an index of performance in simple and compl

SUBMITTER: Statsenko Y 

PROVIDER: S-EPMC8634589 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature