Occupational exposure to high-level disinfectants and risk of miscarriage among nurses.

ABSTRACT:

Objectives

To examine the association of occupational exposure to high-level disinfectants (HLDs) with risk of miscarriage among nurses.

Methods

Our study included women who enrolled in the Nurses' Health Study 3 (2010-2020) and had at least one pregnancy during follow-up. Occupational exposure to HLDs was self-reported at baseline. Every 6 months, a follow-up questionnaire was sent to participants asking for detailed information on pregnancies. We used a discrete-time Cox model to calculate the HRs and 95% CIs of miscarriage according to exposure to HLDs.

Results

Our study included 2579 nurses with a median of 5.6 years of follow-up (range: 1-9 years), and we documented 768 (19%) cases of miscarriage among 3974 pregnancies. Compared with women with no HLD exposure, t

SUBMITTER: Ding M 

PROVIDER: S-EPMC8634624 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature