Satiety does not alter the ventral striatum's response to immediate reward in bulimia nervosa.

ABSTRACT: Individuals with bulimia nervosa (BN) cycle between periods of binge-eating and compensatory behavior and periods of dietary restraint, suggesting extremes of under and overcontrol that may be metabolic-state related. This study examined the influence of hunger and satiety on impulsivity and neural responding during decision-making. Twenty-three women remitted from BN (RBN) and 20 healthy comparison women (CW) performed a delay discounting task after a 16-hr fast and following a standardized meal during functional neuroimaging. A dual-systems approach examined reward valuation (decision trials where the early reward option was available immediately) and cognitive control (all decision trials). Interactions of Group × Visit (Hungry, Fed) for immediate reward revealed that CW had greater act

SUBMITTER: Bischoff-Grethe A 

PROVIDER: S-EPMC8634799 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature