Impact of Tumor-Stroma Ratio on the Prognosis of Colorectal Cancer: A Systematic Review.

ABSTRACT:

Background

It is critical to develop a reliable and cost-effective prognostic tool for colorectal cancer (CRC) stratification and treatment optimization. Tumor-stroma ratio (TSR) may be a promising indicator of poor prognosis in CRC patients. As a result, we conducted a systematic review on the predictive value of TSR in CRC.

Methods

This study was carried out according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 guideline. An electronic search was completed using commonly used databases PubMed, CENTRAL, Cochrane Central Register of Controlled Trials, and Google scholar till the last search up to May 30, 2021. STATA version 13 was used to analyze the data.

Results

A total of 13 studies [(12 for disease-free survival (DFS) and ni

SUBMITTER: Gao J 

PROVIDER: S-EPMC8635241 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature