Hypertensive disorders in pregnancy and child development at 36 months in the All Our Families prospective cohort study.

ABSTRACT: Hypertensive disorders in pregnancy (HDP) are associated with increased risk of offspring neurodevelopmental disorders, suggesting long-term adverse impacts on fetal brain development. However, the relationship between HDP and deficits in general child development is unclear. Our objective was to assess the association between HDP and motor and cognitive developmental delay in children at 36 months of age. We analyzed data from the All Our Families community-based cohort study (n = 1554). Diagnosis of HDP-gestational or chronic hypertension, preeclampsia, or eclampsia-was measured through medical records. Child development was measured by maternal-report on five domains of the Ages and Stages Questionnaire (ASQ-3). Standardized cut-off scores were used to operationalize binary variables fo

SUBMITTER: Scime NV 

PROVIDER: S-EPMC8635344 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature