Circulation of dengue serotype 1 viruses during the 2019 outbreak in Dar es Salaam, Tanzania.

ABSTRACT: Dengue is an important mosquito-borne viral disease in humans in tropical and subtropical countries. In 2019, a total of 6917 dengue cases were reported in Tanzania based on serological analysis. The aim of this study was to confirm the presence of dengue virus (DENV) and conduct its genetic characterization. A total of 191 serum samples were collected from the outpatients seeking care from health facilities in Kinondoni and Ilala districts between March and May 2019. All the samples were initially tested for the presence of non-structural protein 1 and anti-DENV immunoglobulin G (IgG) and IgM using a commercial OnSite Duo Dengue Ag-IgG/IgM rapid test. Of the 191 sera, 110 (57.6%) were DENV seropositive. The presence of DENV ribonucleic acid was confirmed in 18.2% of the seropositive sera

SUBMITTER: Mwanyika GO 

PROVIDER: S-EPMC8635661 | biostudies-literature | 2021 Oct-Dec

REPOSITORIES: biostudies-literature