Characterization and Comparative Genomics Analysis of lncFII Multi-Resistance Plasmids Carrying bla _{CTX - M} and Type1 Integrons From Escherichia coli.

ABSTRACT: This research aimed to investigate the presence and transferability of the extended-spectrum β-lactamase resistance genes to identify the genetic context of multi-drug resistant (MDR) loci in two Escherichia coli plasmids from livestock and poultry breeding environment. MICs were determined by broth microdilution. A total of 137 E. coli resistant to extended-spectrum β-lactam antibiotics were screened for the presence of the ESBL genes by PCR. Only two E. coli out of 206 strains produced carbapenemases, including strain 11011 that produced enzyme A, and strain 417957 that produced enzyme B. The genes were bla _KPC and bla _NDM , respectively. The plasmids containing bla _{CTX - M} were conjug

SUBMITTER: Zhou W 

PROVIDER: S-EPMC8637017 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature