Meningococcal Disease Burden in India: A Systematic Review and Meta-Analysis.

ABSTRACT:

Objective

To perform systematic review and meta-analysis of meningococcal disease burden in India.

Methods

We searched publications on meningococcal disease in India between 1996 and 2020 using PubMed and Google Scholar. Prevalence (proportion) of Meningococcal meningitis and Case-fatality ratio (CFR) were pooled using random effects model. Other outcomes were pooled qualitatively.

Results

The prevalence of Meningococcal meningitis in epidemic and endemic conditions was 12.1% (95% CI: 5.2-21.4) and 0.76% (95% CI: 0.3-1.4), respectively, with a CFR of 12.8% (95% CI: 6.8-20.4) in epidemic settings; N. meningitis caused 3.2% (95% CI: 1.6-5.3) of Acute Bacterial Meningitis (ABM) cases in endemic settings. The disease appeared in infants, adolescents,

SUBMITTER: Ghia CJ 

PROVIDER: S-EPMC8637695 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature