Validation of the predictive accuracy of health-state utility values based on the Lloyd model for metastatic or recurrent breast cancer in Japan.

ABSTRACT:

Introduction

Although there is a lack of data on health-state utility values (HSUVs) for calculating quality-adjusted life-years in Japan, cost-utility analysis has been introduced by the Japanese government to inform decision making in the medical field since 2016.

Objectives

This study aimed to determine whether the Lloyd model which was a predictive model of HSUVs for metastatic breast cancer (MBC) patients in the UK can accurately predict actual HSUVs for Japanese patients with MBC.

Design

The prospective observational study followed by the validation study of the clinical predictive model.

Setting and participants

Forty-four Japanese patients with MBC were studied at 336 survey points.

Methods

This study consisted of two phases. In the first phase,

SUBMITTER: Iwatani T 

PROVIDER: S-EPMC8638153 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature