Genome-wide association study of periodontal pocketing in Finnish adults.

ABSTRACT:

Background

A genome-wide association study is an analytical approach that investigates whether genetic variants across the whole genome contribute to disease progression. The aim of this study was to investigate genome-wide associations of periodontal condition measured as deepened periodontal pockets (≥ 4 mm) in Finnish adults.

Methods

This study was based on the data of the national Health 2000 Survey (BRIF8901) in Finland and the Northern Finland Birth Cohort 1966 Study totalling 3,245 individuals. The genotype data were analyzed using the SNPTEST v.2.4.1. The number of teeth with deepened periodontal pockets (≥ 4 mm deep) was employed as a continuous response variable in additive regression analyses performed separately for the two studies and the results were combined i

SUBMITTER: Tegelberg P 

PROVIDER: S-EPMC8638186 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature