Overt speech critically changes lateralization index and did not allow determination of hemispheric dominance for language: an fMRI study.

ABSTRACT:

Background

Pre-surgical mapping of language using functional MRI aimed principally to determine the dominant hemisphere. This mapping is currently performed using covert linguistic task in way to avoid motion artefacts potentially biasing the results. However, overt task is closer to natural speaking, allows a control on the performance of the task, and may be easier to perform for stressed patients and children. However, overt task, by activating phonological areas on both hemispheres and areas involved in pitch prosody control in the non-dominant hemisphere, is expected to modify the determination of the dominant hemisphere by the calculation of the lateralization index (LI).

Objective

Here, we analyzed the modifications in the LI and the interactions between cognitive net

SUBMITTER: Berro DH 

PROVIDER: S-EPMC8638205 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature