Prevalence and burden of multiple sclerosis-related fatigue: a systematic literature review.

ABSTRACT:

Background

Multiple sclerosis (MS) is a chronic, demyelinating disease of the central nervous system that results in progressive and irreversible disability. Fatigue is one of the most common MS-related symptoms and is characterized by a persistent lack of energy that impairs daily functioning. The burden of MS-related fatigue is complex and multidimensional, and to our knowledge, no systematic literature review has been conducted on this subject. The purpose of this study was to conduct a systematic literature review on the epidemiology and burden of fatigue in people with multiple sclerosis (pwMS).

Methods

Systematic searches were conducted in MEDLINE, Embase, and Evidence-Based Medicine Reviews to identify relevant studies of fatigue in pwMS. English-language records publ

SUBMITTER: Oliva Ramirez A 

PROVIDER: S-EPMC8638268 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature