Is titanium alloy Ti-6Al-4 V cytotoxic to gingival fibroblasts-A systematic review.

ABSTRACT:

Objectives

Grade V titanium alloy (Ti-6Al-4 V) is a well-recognized metallic biomaterial for medical implants. There has been some controversy regarding the use of this alloy in medical devices in relation to the toxicity of vanadium. In Dentistry, Ti-6Al-4 V remains prevalent. This systematic review aims to evaluate the effects of Ti-6Al-4 V on cells relevant to oral environments such as gingival fibroblasts.

Materials and methods

A literature search was undertaken for relevant English language publications in the following databases: Dental and Oral Science, Medline and Web of Science. The electronic search was supplemented with a search of references.

Results

After application of inclusion and exclusion criteria. A total of eight papers are included in this review.

SUBMITTER: Willis J 

PROVIDER: S-EPMC8638288 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature