The effect of inbreeding, body size and morphology on health in dog breeds.

ABSTRACT:

Background

Dog breeds are known for their distinctive body shape, size, coat color, head type and behaviors, features that are relatively similar across members of a breed. Unfortunately, dog breeds are also characterized by distinct predispositions to disease. We explored the relationships between inbreeding, morphology and health using genotype based inbreeding estimates, body weight and insurance data for morbidity.

Results

The average inbreeding based on genotype across 227 breeds was F_adj = 0.249 (95% CI 0.235-0.263). There were significant differences in morbidity between breeds with low and high inbreeding (H = 16.49, P = 0.0004). There was also a significant difference in morbidity between brachycephalic breeds and non-brachycephalic breeds (P = 0.0048) an

SUBMITTER: Bannasch D 

PROVIDER: S-EPMC8638537 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature