Angiotensin II receptor blockers and oral squamous cell carcinoma survival: A propensity-score-matched cohort study.

ABSTRACT:

Objectives

Angiotensin II receptor blockers (ARBs) improve the survival rates of patients with various cancers. However, it remains unclear whether ARBs confer a survival benefit on patients with oral squamous cell carcinoma (OSCC). Here, we assessed the associations between ARB use and survival in patients with OSCC of different stages.

Materials and methods

This was a 10-year retrospective cohort study of OSCC patients. We enrolled 7,558 patients diagnosed with oral cancer between January 2007 and December 2017 whose details had been entered into the Chang Gung Research Database. Seven hundred and fourteen patients were recruited from the Chang Gung Research Database after performing 1:1 propensity score-matching between ARB users and non-users. Cox's regression models wit

SUBMITTER: Wu CN 

PROVIDER: S-EPMC8638984 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature