Mechanical Pain Sensitivity in Postamputation Pain.

ABSTRACT:

Objectives

Postamputation, clinical markers of pain-related peripheral and central nervous system hypersensitivity remain understudied. This study aimed to identify whether adults with postamputation pain demonstrate greater pain sensitivity in primary (ie, amputated region) and secondary (ie, nonamputated region) sites, as compared with pain-free peers and controls with intact limbs.

Methods

Ninety-four participants postunilateral, transtibial amputation (59 with pain, 35 pain-free) and 39 controls underwent pain-pressure threshold (PPT) testing at 10 sites. Pain-pressure thresholds were normalized to sex-specific control data using Z score conversions. Normalized primary-site and secondary-site PPTs were compared between groups using multivariate analysis of variance (P<0.

SUBMITTER: Beisheim-Ryan EH 

PROVIDER: S-EPMC8639794 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature