Chlorogenic acid: Potential source of natural drugs for the therapeutics of fibrosis and cancer.

ABSTRACT: Fibrosis and cancer is described by some epidemiological studies as chronic stages of different disease conditions typically characterized by uncontrolled accumulation of extra-cellular matrix (ECM), thereby leading to inflammation of tissues and organ (lungs, heart, liver and kidney) dysfunction. It is highly prevalent, and contributes to increased mortality rate worldwide. Currently, the therapeutical approaches involving selected medications (bemcentinib, pirfenidone and nintedanib) obtained synthetically, and used in clinical practices for fibrosis and cancer management and treatment has shown to be unsatisfactorily, especially during progressive stages of the disease. With regards to finding a more potent, effective, and promising curative for fibrosis and cancer, there is need for co

SUBMITTER: Nwafor EO 

PROVIDER: S-EPMC8640119 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature