Statin Discontinuation and Cardiovascular Events Among Older People in Denmark.

ABSTRACT:

Importance

Statin use is common in older persons. Given uncertainties in ongoing benefit, changes in health status, and shifting goals of care and preferences, statin discontinuation may be considered in some older persons, although there is currently little evidence to guide this decision.

Objective

To evaluate the association between statin discontinuation and the rate of major adverse cardiovascular events (MACE) among people aged 75 years or older who receive long-term statin treatment.

Design, setting, and participants

This cohort study included all persons in Denmark aged 75 years or older who were treated with statins for at least 5 consecutive years as of January 1, 2011. Participants were followed up until December 31, 2016. Data were analyzed from July to No

SUBMITTER: Thompson W 

PROVIDER: S-EPMC8640890 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature