Brain metastases: increasingly precision medicine-a narrative review.

ABSTRACT:

Objective

To broadly review the modern management of brain metastases.

Background

Brain metastases are the commonest neurological manifestation of cancer and a major cause of morbidity in cancer patients. Brain metastases are increasing in frequency, as a result of longer life expectancy of cancer patients, more sensitive methods for brain metastasis detection and an ageing population. The proportional incidence of brain metastases according to cancer of origin, from greatest to least, is lung cancer, melanoma, renal, breast and colorectal cancers. Patients with lung cancer and melanoma are most likely to have brain metastases at diagnosis. Brain metastases cause a variety of symptoms, depending on their size and location, whether they cause mass effect and oedema, compressi

SUBMITTER: McKay MJ 

PROVIDER: S-EPMC8640905 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature