Navigating with grid and place cells in cluttered environments.

ABSTRACT: Hippocampal formation contains several classes of neurons thought to be involved in navigational processes, in particular place cells and grid cells. Place cells have been associated with a topological strategy for navigation, while grid cells have been suggested to support metric vector navigation. Grid cell-based vector navigation can support novel shortcuts across unexplored territory by providing the direction toward the goal. However, this strategy is insufficient in natural environments cluttered with obstacles. Here, we show how navigation in complex environments can be supported by integrating a grid cell-based vector navigation mechanism with local obstacle avoidance mediated by border cells and place cells whose interconnections form an experience-dependent topological graph of t

SUBMITTER: Edvardsen V 

PROVIDER: S-EPMC8641373 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature