Vitamin D Supplement Use and Risk of Breast Cancer by Race-Ethnicity.

ABSTRACT:

Background

Vitamin D has anticarcinogenic properties, but a relationship between vitamin D supplement use and breast cancer is not established. Few studies have accounted for changes in supplement use over time or evaluated racial-ethnic differences.

Methods

The Sister Study is a prospective cohort of 50,884 women with 35-74 years of age who had a sister with breast cancer, but no breast cancer themselves at enrollment (2003-2009). We used Cox proportional hazards models to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) for the association between vitamin D supplement use and incident breast cancer (3,502 cases; median follow-up 10.5 years).

Results

Vitamin D supplement use was common, with 64% reporting ever use (at least once per month) in the year

SUBMITTER: O'Brien KM 

PROVIDER: S-EPMC8641477 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature